It is possible to identify CRM strategies, practices, and solutions that strengthen and support knowledge management approaches, especially in a more complex and diversified environment such as the one where multinational organizations are inserted. Regarding knowledge about customers, the adoption of customer-focused strategies supported by CRM systems can significantly strengthen the learning capabilities of MNCs’ subsidiaries. These capabilities reflect on MNC headquarters in the form of increased corporate capacity to identify local and global trends concerning customers’ preferences, cultural aspects, needs, and consumer behavior. This knowledge subsidizes the elaboration of more effective global strategies by multinational organizations.