Salmonella is an important concern to the poultry industry mainly because of the associated contamination of poultry products for human consumption. With the EU ban on sub-therapeutic antibiotic usage in livestock industry, there is increasing interest in finding alternatives to antibiotics for poultry production. Passive immunization is one of those strategies. Egg yolk antibody prophylaxis and therapy have a natural place in poultry industry. In poultry, maternal antibodies are transmitted to the offspring via the yolk of the egg.