The most significant effects in our study were in the group of
men with combined exercise and dietary intervention. This
group not only decreased anthropometric parameters and serum
AGEs, but also improved the lipid profile with reduction of TGs
and an increase in HDL levels. We do not find any previous re-
ported studies examining the combined effect of exercise and an
AGE-restricted diet without caloric restriction; and this signifi-
cance remained when we evaluated the differences within and
between groups. Main limitations of our study were the rela-
tively small number of participants and a significant percent of
dropouts who could not be invited for assessment at the end of
the intervention as a control. Moreover, all the participants were
men, which limits its generalizability, and perhaps more
importantly, the intensity of the exercise might have not been
sufficient to elicit significant metabolic changes.