The patient is kept in a quiet room with minimal stimulation. Control of spasms and prevention of hypoxic episodes are crucial. Diazepam or another anxiolytic is useful ( 0.6-1.2mg/kg/d intravenousty in six divided doses ). In the newborn, two or three divided doses should be given. Large doses ( up to 25 mg/kg/d ) may be required for older children. Diazepam is given intravenously until muscular rigidity much less prominent. The drug may then be given orally and the dosage reduced as the child improves. Mechanical ventilation and muscle paralysis are necessary in severe cases. Nasagastric or intravenous feedings should be used to limit stimulation of feedings and prevent aspiration.