In this paper, response surface methodology was employed to optimize experimental process for ionic
liquid based ultrasonic assisted extraction of curcuminoids compounds from rhizomes of Curcuma longa
L. The Box–Behnken design on three factors and five levels together with response surface methodology
were used to optimize experimental conditions for total curcuminoids content and radical scavenging
capacity. The radical scavenging capacity was determined by ABTS and TRAP methods. For the ionic
liquid based ultrasonic assisted extraction, optimum process was set as below: [Omim]Br concentration,
4.2 mol/L; liquid-raw ratio, 30 mL/g; extraction time, 90 min; ultrasonic power, 250W.
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