Prophylaxis of leukopenia : In rabbits with leucopenia caused by whole body X-ray irradiation (600 roentgen), the total alkaloids (30 mg/kg) and oxymatrine (100 mg/kg) showed a significant therapeutic effect when given intravenously or intramuscularly, but matrine was not effective. In rabbits with leucopenia elicited by 60Co irradiation, 500 roentgen/min, oxymatrine had no therapeutic effect when the dose of 120 roentgen/min was used, but it showed preventive and therapeutic effects at 31 roentgen/min.