The physical and rheological properties and stability of the MFC-stabilized o/w emulsions were strongly influenced by the concentration of MFC. An increase in MFC concentration led to larger droplets, darker and more color, more pronounced elastic responses, and higher stability to creaming of the emulsions. However, all emulsions, regardless of the MFC concentration used, possessed long-term storage stability against droplet coalescence. A possible mechanism of MFC for o/w emulsion formation and stabilization could be due to the adsorption of MFC at the oil-water interfaces, providing a steric (mechanical) barrier against droplet coalescence by the Pickering mechanism. Additionally, with an increase in MFC concentration, the formation of a three-dimensional network of the excess MFC particles in the continuous aqueous phase immobilized the droplets thereby preventing creaming. This study attempts to provide practical information that may increase the utilization of MFC as natural emulsifying and stabilizing ingredients in food products such as salad dressings, whipped toppings, and sauces. In terms of nutritional profile, MFC, like cellulose and other cellulose derivatives, is essentially non-caloric dietary fibers which provides many health benefits.