Interestingly
enough, CRS was the first human pathology in which the
accumulation of ILC2 in inflamed tissues was clearly shown
[119]. Although allergic rhinitis is classically viewed as a Th2-
skewed pathology, recent studies have shown the upregulation
of Th17-specific parameters in local mucosa and
peripheral blood of patients, which correlatedwith eosinophilia
and symptom severity