1. Identify each main process of the transfusion chain
2. Identify the frequency or usage factor of each main process along the transfusion chain (e.g., administering and monitoring
transfusion in the hospital unit)
3. Identify all activity steps behind each main process along the transfusion chain
4. Identify the usage factor of each activity step relative to the main process
5. Capture the time required for each activity step
6. Identify the costs of all resources consumed in each activity step
7. Populate database with all information captured
8. Apply formula (Fig. 1A) to determine the process cost per each RBC unit transfused
9. Transfer the database electronically into ARIS Business Optimizer and compute the process cost of transfusion by
• Labor cost
• Material cost
• Third-party cost
• Capital cost
10. Add all transfusion-related direct overhead costs (e.g., blood bank accreditation fees, undergraduate and postgraduate education)
11. Add all hospital indirect overhead costs (derived from percentage