The biopsy injury to the prostate must heal and for this are inflammatory mediators and growth hormones needed. But precisely these mediators produce in a less vicious tumor a faster and aggressive growth of the tumor and thus feed a general activation. Therefore, we offer our patients, currently, an injury-free diagnosis of prostate cancer, that is to say we replace when needed the biopsy with molecular genetic testing and appropriate imaging techniques. One can also abstain from the traumatizing biopsy because even for a positive diagnosis is usually only a „Watchful Waiting” recommended. So why should a man risk a carry-over of tumor cells, or tumor activation, or even a local infection, if they have no therapeutic consequences.