REPERFUSION AND CLOSURE - Prior to reperfusion, administer systemic methylprednisolone. Remove any topical cooling from the chest. Partially release the pulmonary arterial clamp to flush the preservative solution and ventilate the implanted lung to de-air the pulmonary vascular bed. Remove the pulmonary vein clamp gradually in order to maintain adequate systemic perfusion and secure the venous suture line.