. There was a significantly greater reduction in
inflamed lesions in the benzoyl peroxide group at all three
follow-up visits. Skin discomfort during treatment was
reported less frequently in the TTO group than in those using
benzoyl peroxide (44% versus 79%). Without a placebo
group it is difficult to decide whether this study demonstrates
the presence or absence of a treatment effect and it may also
have lacked statistical power to test equivalence between the
two therapies.