Microorganisms can use free cells or immobilized cells for reducing the color. When comparing it, free cells have a leakage and obstruction of cells while immobilized cells have a high effective and no leakage and obstruction. The popular technique used is Entrapment which is available to all microorganisms but it has the limitation of cell loading and cell leakage. The other technique is Encapsulation. It has not the limitation of cell loading but it causes to be the weak beads. The problem of Entrapment and Encapsulation cause the development a new technique for immobilization cells by integration two methods together which is Hybrid Immobilization. Beads from this technique are highly effective, no limitation of cell loading, and can protect the leakage of cells.