The use of inhibitors of the opening of mitochondrial
MPTP (like UDCA) in cases where there is apoptosis,
and of glutathione precursors (like NAC and S-adenosylmethionine) in cases of oxidative stress or glutathione depletion have been suggested as therapeutic strategies in
cases of hepatotoxicity (60). A beneficial effect of
UDCA has been observed in hepatitis induced by amoxycillin, non-steroidal anti-inflammatory drugs, and sulfamide (61).