Acidification to the isoelectric point of meat proteins (pH 5.3 to 5.4) and the increase of the ionic strength induces gel formation of the proteins and thus confers important structural changes. The high levels of sodium chloride and lactate in fermented sausages contribute to the development of the characteristic taste of the product. Rapid acidification and subsequent drying are of paramount importance for inhibition of the growth of pathogens and their subsequent inactivation during ripening. As there exist nondried fermented sausages of a spreadable type (e.g., in Germany, known as Streichmettwurst, Teewurst, Rohpolnische), the highest hygienic standards of the raw materials and production facilities are key to product safety. In addition to low pH and water activity, specific microbial metabolites such as diacetyl or short chain fatty acids exert an inhibitory effect towards pathogens. Several meat starter cultures produce bacteriocins small, heat stable peptides with antimicrobial activity .The use of bacteriocinogenic starters has been shown to contribute to the elimination of Listeria during sausage fermentation. However, because of the resistance of Gram-negative organisms, including Salmonella and Escherichia coli o157:H7 strains, the contribution of bacteriocins to the overall hygienic safety fermented meats is limited