Cancer stem-like cells (CSCs) are defined as rare cells
in malignant tumours with the ability to self-renew and to
differentiate into various heterogeneous cancer cell lineages
[2]. Abnormal gene expression in CSCs might be responsible
for the acquisition of various genetic and epigenetic
events and may play a critical role in tumour initiation,
maintenance, progression, lymphatic involvement, distant
metastasis, and chemoradiotherapy resistance [