Renal replacement therapy for ARF generally involves intermittent hemodialysis (IHD) or continuous renal replacement therapy (CRRT), e.g., continuous veno-veno-hemofiltration (CVVH). Since the hemodynamic stress is less with CVVH than with IHD, it is possible that any additional hemodynamic or nephrotoxic insult, which might prolong the course of ARF and thereby increase mortality, might be less with CRRT. The most recent metaanalysis, however, of randomized results comparing IHD with CRRT in ARF has not shown any difference in survival (72).