Black people in the UK, in the Caribbean,
and to a lesser extent in the USA, experience coronary heart disease events at different rates than white
people. Despite having higher prevalence of hypertension, cigarette smoking and diabetes, black males
have significantly lower coronary heart disease rates
than white males, whereas no significant differences
have been detected in females. The only known risk
factor differences that could account for the difference in CHD rates are higher HDL cholesterol and
lower triglycerides that are seen in blacks compared
with whites. Obesity and, in particular abdominal
obesity, seems to determine TG and HDL cholesterol
levels: black males are less centrally obese than
whites, while total adiposity and central distribution
of fat is more predominant in black females compared
with white females. We propose that the less degree of
abdominal adiposity observed in black males is related with an increased anti-lipolytic effect of insulin,
which could account for low triglycerides and high
HDL cholesterol levels, and consequently explain the
higher protection from coronary heart disease experienced by black males compared with whites and black
females.
Black people in the UK, in the Caribbean,and to a lesser extent in the USA, experience coronary heart disease events at different rates than whitepeople. Despite having higher prevalence of hypertension, cigarette smoking and diabetes, black maleshave significantly lower coronary heart disease ratesthan white males, whereas no significant differenceshave been detected in females. The only known riskfactor differences that could account for the difference in CHD rates are higher HDL cholesterol andlower triglycerides that are seen in blacks comparedwith whites. Obesity and, in particular abdominalobesity, seems to determine TG and HDL cholesterollevels: black males are less centrally obese thanwhites, while total adiposity and central distributionof fat is more predominant in black females comparedwith white females. We propose that the less degree ofabdominal adiposity observed in black males is related with an increased anti-lipolytic effect of insulin,which could account for low triglycerides and highHDL cholesterol levels, and consequently explain thehigher protection from coronary heart disease experienced by black males compared with whites and blackfemales.
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