Microorganisms require moisture, food and time at a suitable temperature for growth. Nutrition for microbial growth is in abundance in food processing facilities, as is time (particularly in areas inaccessible to routine cleaning and sanitation, such as bolted, sandwiched structures that are not routinely taken apart for cleaning). Manufacturing plant environmental temperatures are often in a range suitable for microbial growth. Such growth is also determined by other factors such as oxidation-reduction potential, temperature, presence or absence of inhibitors, and interaction between microbial populations. Microorganisms cannot grow in environments without adequate moisture. Hence, moisture control in the factory environment is the most critical factor influencing microbial growth in the factory environment.