Antibiotics are medicines that are used to prevent and treat infections caused by bacteria and certain parasites. The process of antibiotics that has both benefits and disadvantages. Antibiotic resistance is increasing in all parts of the world due to dangerous resistant mechanism antibiotics in treatment of infectious threats ability. In countries where antibiotics can be bought without a prescription to spread of resistance is made worse. Mechanism of resistance to emerging and spreading around the world that threaten our ability in the treatment of infected result in illness for a long time, disability and death. Health agencies such as the government, Department, or the public network cannot be ignored anymore. Because not only the people affected. But from now on is woe share of humanity. The World Health Organization repeat issues that have always found bacteria drug resistance 10 increased throughout the years. Drug-resistant infection situation is entering a crisis stage, especially in the antibiotic group. Because there are new types of medicines less.