Xa solution was
prepared under stirring by dissolving 6.5 g of dried powder
into 1 l distilled water. The Xa–CS hydrogels were prepared
as capsules in the following way: 880 ml of the
previously degassed Xa solution were added dropwise
through a syringe needle (1.1 mm diameter) using a peristalic
pump (flow rate 3 ml/min) to 400 ml of CS solution.