At the end of the study, the level of serum NO increased significantly in treatment groups compared to both positive and negative control groups (Figure 5). Treatment group of Kadukmy-2™ showed increase in NO concentration by almost five fold in SHR. The MDA levels reduced significantly in Kadukmy™ treated group Kadukmy-1™ and Kadukmy-2™ mg/kg compared to positive control group and baseline MDA level (Figure 6). The negative control group showed the lowest MDA level and statistically significant compared to positive control group and treated group Kadukmy-0.5™. It indicated that Kadukmy™ treated group with Kadukmy-1™ and
Kadukmy-2™ were able to reduce oxidative stress levels.