Chitosan is both biocompatible and bacteriostatic [42] and has
been shown to promote wound healing [43,44]. In this study, chitosan
was modified to form CEC. Unlike native chitosan that is only
soluble in acidic condition, CEC is soluble at physiological pH and
mixing it with Odex at the same pH produces a chitosan containing
hydrogel precursor (Fig. 1) capable of fully conforming to the application
site before congealing.