Although many questions about the toxic effects of
inhalants in general are unresolved, the nervous system
is clearly vulnerable to toxicity from these substances
(4). Organic solvents may produce encephalopathy,
cerebellar dysfunction, optic and other cranial neuropathies,
parkinsonism, and peripheral neuropathy (1, 4,
5). Both acute and chronic encephalopathies are common
(1). Of all the inhalants, the greatest incidence of
abuse of a single substance is found with toluene,
prompting many human and animals studies on the specific
effects of this compound