In the Mae Sot District, Tak Province of Thailand, farmers irrigating crops using water Mae Tao and Mae Ku creeks, which have a zinc mine in the catchment, have been exposed to cadmium contaminated rice and water over a long period of time. An epidemiological study revealed that persons who mainly consumed rice grown in contaminated fields around Mae Sot had higher urinary cadmium than those who did not. cadmium intoxication has been managed by metal chelating compounds, but there are numerous undersirable side effects.