In this work, we present the design, fabrication and characterization of a silicon-based device dedicated for activation of
biological solution under dynamic and static flow regimes by fluid mixing using acoustic low-frequency vibrations. The acoustic
vibrations are generated by a bulk piezoelectric lead-zirconate-titanate (PZT). In the dynamic flow regime, biological compounds
(as antibodies) were used in order to build immunochips taking advantages from the remarkable properties of such acoustic
device to optimize the efficiency of Abs grafting onto chemically functionalized chip. The evaluation of the performance of the
system to mix and activate fluids is presented. The experiments show the mixing capacity of the device in static and dynamic
flow regimes using colored water and a biological model respectively.