The present study examined the changes in the fragility of camel and donkey erythrocytes caused by
variations in temperature, pH and blood storage. Although the fragility did not differ between sexes in both
species, camel erythrocytes were more osmotically resistant than donkey erythrocytes. At a constant pH of
7.4, the fragility decreased in the camel but increased in the donkey at lowered temperatures. However, at a
constant temperature of 28 ºC, the fragility of camel and donkey erythrocytes increased in an acidic solution and
decreased in an alkaline solution. Additionally, blood storage for 24 hours at 4 ºC increased the fragility of camel
erythrocytes, but not donkey erythrocytes. However, the erythrocyte fragility increased in both species after 48
or 72 hours of blood storage at 4 ºC. In conclusion, our results suggest that variation in the temperature and pH
of the erythrocyte environment and duration of blood storage may each play a signifi cant role in the osmotic
behaviour of camel and donkey erythrocytes