The report, published in the Journal of the American Medical Association (AMA), was based on the researchers' earlier research but also includes a review of own studies over the past few years. The American Medical Association represents about half of all US and is strong opponent of smokin The study doctors uggests that people who smoke cigarettes are continually damaging their'cardiovascular system, which adapts in order to compensate for the effects of smoking it further states that people who. do not smoke do not have the benefit of their system adapting to the smoke inhalation. Consequently, the effects of passive smoking are far greater on non-smokers than on smokers.