Multifunctional nanomaterials can be modified with
specific biomolecules to increase drug loading
capacity and target specific proteins, DNA sequences,
and other macromolecular structures.1-5 However,
one common limitation of nanoparticle applications in clinical
settings is the difficulty of tracking nanoparticle localization
and movement in vivo. Consequently, development of
techniques for facile and effective labeling of nanoparticles
with imaging agents would greatly improve the utility of
nanoparticle systems.