In the Ayutthaya period the area of Samut Songkhram was known as "suan nok" (Thai สวนนอก, "outer garden") and was administered by Ratchaburi. During the reign of King Taksin it was made a province. It was the birthplace of Queen Amarindra of King Rama I. The birthplace of King Rama II in Amphawa district is now a memorial park.
The provincial seal shows a drum over a river. The Thai word for drum is klong, thus refers to the Mae Klong River, as well as the old name of the province, Mae Klong. On both sides of the river coconut trees are displayed as one of the main product of the province.
Provincial tree is Casuarina equisetifolia.