In a study by Sangster (1987), methyl chavicol (100 μg; 0.675 μmol) administered orally to humans was eliminated primarily in the urine and as CO2 in expired air. 65% of the total dose was recovered in urine and examined. No amount of methyl chavicol could be detected in urine. Methyl chavicol was completely metabolized by oxidative O-demethylation, and various oxidations of the side chain. In urine, six metabolites were identified:[