The parameterized metaheuristic scheme is used and adapted here to the
problem of estimation of the kinetic parameters in a chemical reaction. Four pure metaheuristics (GRASP, Tabu
Search, Genetic algorithm and Scatter Search) are included in the parameterized scheme, which allows us to experiment
with the basic metaheuristics and their combinations/hybridizations. Experiments have been conducted
with a total of fifteen metaheuristics (basics and combinations); the initial solution is improved and the preferred
method for this problem is analysed