the appearance of Carbopol 940 viscous solution became ivory white, which was in accordance with the results obtained by Chen et al. [36]. The possible reason is thatthe dehydration of some ingredients such as surfactant and co-surfactant in ME makes Carbopol 940 dissociated from hydratedstate. The prepared hydrogels of sertconazole nitrate microemul-sion were subjected for drug content, viscosity