The purpose of this study was to determine the concentration of biologically active compounds
(polyphenols and L-ascorbic acid) in Rosa canina L. and Rosa rugosa Thunb. wines. The antioxidant
capacity and antimutagenicity of the wines were also investigated. Aged and young wines contained
phenolics levels of 2786–3456 and 3389–3990 mg/L GAE, respectively. The final concentrations of
ascorbic acid were 1200 for Rosa rugosa Thunb. and 600 mg/L for Rosa canina L. R. rugosa and R. canina
wines revealed high antioxidant activity in different assays (with ABTS, DPPH, and DMPD radicals).
Expressed in terms of Trolox equivalent antioxidant capacity (TEAC), the activity ranged from 8 to
13.5 mM. Significant differences were found between the tested wines terms of their reactivity against
the ABTS and DMPD radicals. The wines inhibited in vitro N-methyl-N0-nitro-nitrosoguanidine (MNNG)
and the number of induced His+ revertants increased in a dose-dependent manner by 16–48% in
Salmonella Typhimurium TA98 and 12–52% in Salmonella Typhimurium TA100. Wines from dog rose
(Rosa canina L.) showed a greater ability to reduce mutations