For patients with pre-existing cardiac or pulmonary conditions, monitor more frequently
throughout the infusion and the post-infusion period since they may be at greater risk of
experiencing more severe reactions. Hypotension may occur as part of the GAZYVA infusion
reaction. Consider withholding antihypertensive treatments for 12 hours prior to, during each
GAZYVA infusion, and for the first hour after administration until blood pressure is stable. For
patients at increased risk of hypertensive crisis, consider the benefits versus the risks of
withholding their hypertensive medication as is suggested here.