Extemporaneous Preparations A 2 mg/mL oral omeprazole solution (Simplified Omeprazole Solution) can be prepared with five omeprazole 20 mg delayed release capsules and 50 mL 8.4% sodium bicarbonate. Empty capsules into beaker. Add sodium bicarbonate solution Gently stir (about 15 minutes) until a white suspension is formed. Transfer to amber-colored syringe or bottle. Stable for 14 days at room temperature or for 30 days under refrigeration.