It is commonly considered that the increase in pressure results in an increase in CO2 density, increasing the solvating power of the supercritical fluid. Thus, higher pressure is responsible for quantitative recoveries and stronger interactions between the fluid and the matrix. It can be observed that an increase in operating pressure from 20 to 40 MPa resulted in a steady increase in lycopene yield in our study. The results were also consistent with those reported by Topal et al. (2006).