From Table 2 we can see that both doses of pumpkin seed powder 3.8g/kg bw (k=1.219) and 7.6g/kg
bw(k=1.347) produced a medium immunostimulation effect.
The carbon particles injected into the mice is primarily phagocytised by liver macrophages (90%) followed by
spleen and thymus gland macrophages (10%)1. The carbon particles are eliminated in the liver by fixed macrophages
known as Kupffer cells. The spleen contains macrophages, dendritic cells, T cells and B cells and so responds to
systemic infection and plays a role in both humoral and cellular immunity. The thymus is the site of T cell
development and maturation.