The extraction of pesticides from honey samples can be performed by modified QuEChERS method, because this method is efficient for a wide range of compounds, including highly polar pesticides, with acid and basic features. The clean-up step, called dispersive solid phase extraction (d-SPE), used in QuEChERS methods, allows for quick and simultaneous clean-up with water removal. A final extraction with less polar solvents facilitates the precipitation of polar co-extractives.