The current outbreak of Zika virus (ZIKV) in South America is one of the most serious public health emergencies since the Ebola outbreak of West Africa in 2014. Found ZIKV belongs to the flaviviridae family and has two lineages (Asian and African). The virus was first discovered in Uganda In 1947 from a study of yellow fever yielded the first isolation of a new virus, from the blood of a sentinel rhesus macaque that had been placed when in the Zika Forest of Uganda. Zika virus remained in relative obscurity for nearly 70 years then, within the span of just 1 year, Zika virus can introduced into Brazil from the Pacific Islands and spread rapidly throughout the Americas.