The use of immunostimulants can enhance activities in a
nonspecific defense mechanism, increase resistance to infectious
disease by enhancing innate humoral and cellular defense mechanisms
and indirectly cause growth improvement in fish [1].
Recently, immunostimulants such as probiotics and prebiotics have
shown to be promising as preventive and environmentally friendly
alternatives to antibiotics in aquaculture [2]. Prebiotics are nondigestible
food ingredients that beneficially affect the host by
selectively stimulating the growth and/or activity of one or a
limited number of bacteria in the colon. Intake of prebiotics could
significantly modulate the colonic microbiota by increasing the