MFifteen percent (15%) L-ascorbic acid (Merck,
Darmstadt, Germany) and/or 1% dl--tocopherol (Roche, Nutley, NJ) was formulated in an aqueous
vehicle containing 5% Brij 30 (Uniqema, New Castle,
Del) and 15% ethanol. All solutions were adjusted to
pH 3.2. For the purposes of these experiments, concentrations
of ingredients and pH of the solution
chosen for testing was formulated to provide maximum
percutaneous absorption of L-ascorbic acid
and -tocopherol.
MFifteen percent (15%) L-ascorbic acid (Merck,
Darmstadt, Germany) and/or 1% dl--tocopherol (Roche, Nutley, NJ) was formulated in an aqueous
vehicle containing 5% Brij 30 (Uniqema, New Castle,
Del) and 15% ethanol. All solutions were adjusted to
pH 3.2. For the purposes of these experiments, concentrations
of ingredients and pH of the solution
chosen for testing was formulated to provide maximum
percutaneous absorption of L-ascorbic acid
and -tocopherol.
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