Mimosa pudica:
Mimosa pudica, commonly known as sensitive plant belongs
to family Mimosaceae. Mucilage of M. pudica is obtained
from seeds, which is composed of d-xylose and d-glucuronic
acid. Mimosa seed mucilage hydrates and swells rapidly on
coming in contact with water. Earlier the seed mucilage was
75 evaluated for binding and disintegrating agent .
In a study of mucilage obtained from M. pudica as sustained
release material was investigated. Matrix tablets containing
different proportions of mucilage, dibasic calcium phosphate
as diluent and diclofenac sodium as model drug was
formulated by wet granulation method. The study reveals that
the drug release from the matrix tablet decreases as the
concentration of mucilage increased and followed Higuchi
square root release kinetics. The drug release mechanism was
mainly diffusion for tablets containing higher proportion of
mucilage and a combination of matrix erosion and diffusion
for tablets containing smaller proportion of mucilage. The
study demonstrated that formulation containing mucilage to
drug in the proportion of 1:40 was found to be similar to the
75 commercial sustained-release formulation of diclofenac .