n-hexane and ethanolextracts of Chromolaena odorata, H. capitata and Canangaodorata showed potent activity to inhibit C. albicans growth.The ethanol extract of Chromolaena odorata displayed the high-est activity against C. albicans with AI of 0.37–0.63 relative tonystatin, a commercial antibiotic for treating Candida infection.C. albicans is thought to be the major fungal pathogen of humans[22]. C. albicans accounts for approximately 50% of cases ofcandidemia associated with colonization of indwelling devices,such as catheters, endotracheal tubes, and pacemakers [23,24].Furthermore, infections caused by C. albicans remain the pre-dominant nosocomial fungal infections, due to the increasingpopulation of patients whose immune systems are compromisedby AIDS or immunosuppressant or anticancer therapy [25,26].Limited number of available antifungal drugs and repeatedexposure to these limited antifungal agents led to the rapiddevelopment of drug resistance [27]. Potent activity of the plantextracts against C. albicans suggests the possibility for the treat-ment of candidemia, nosocomial infection, and other Candidainfection-caused diseases