n antisense oligonucleotide (ASO) is a short strand of synthetic DNA or RNA that is designed to bind to a complementary sequence of RNA. The binding of the ASO to the target RNA can have various effects, including blocking the translation of the RNA into a protein, promoting its degradation, or modulating its splicing. ASOs are used in molecular biology and therapeutics to regulate gene expression, and they have shown promise in treating genetic disorders and other diseases by targeting specific RNA molecules involved in the disease process.