Clinical Guidelines (GLs) are one of the manifestations of the
recent emphasis on evidence-based medicine, which tries to
apply the best available evidence gained from scientific methods such as research studies, meta-analyses, and reviews, to support better clinical decision making [1]. Extensive evidence
confirms that state-of-the-art GLs are a powerful method for
standardization and uniform improvement of the quality of
medical care and patient outcomes, often increasing patient
survival rates while reducing the escalating costs of medical
care [2–6]