RESULTS: Human patch tests for cosmetics were performed of
4606 cases, and 3033 subjects participated in each case. The
response in each case was calculated based on total subject number,
skin reaction intensity and the number of respondents. The
calculated response was standardized using the z-score, and a
safety zone was provided in terms of human primary irritation in
accordance with the human skin reaction evaluation criteria and
usage or formula of cosmetics.