A review article of interventions for adherence to antidepressants
showed that the interventions used were primarily focused
on patient education, drug monitoring, and frequency
of visits or phone follow-up. Adherence measures were primarily
self-report and pharmacy refill records. The overall
pharmacist impact on adherence ranged from 1% to 33%.45
The studies included in this meta-analysis did not use more
accurate measures of adherence such as biomarkers and direct
observed therapy