The Peleg equation showed to be suitable to model the
solid–liquid extraction kinetics of total polyphenols from
grape seeds at tested conditions, which was proved by high
correlation coefficient in all experiments (q > 0.994) and
relatively low RMSD (0.3787–1.7490). The 80–90% of total
polyphenols reached within 200 min was extracted in the
first 40 min of extraction. The temperature and particle
size, as well as their interaction had high influence on
solid–liquid extraction kinetics. The values of initial extraction
rate, 1/K1, and extraction extent, 1/K2, increased with
the decrease of the particles size and showed exponential
trend. The extraction temperature had bigger influence on
initial extraction rate and extraction extent for bigger than
for smaller particles, which were proved by the highest
value of energy activation. The results of this work could
contribute in the simulation and optimization of extraction
kinetics for grape seed.