In sub-Saharan Africa, very few studies have been conducted to analyse the influence that different types of buildings have on indoor air quality. In accordance with previous research works, the thermal and hygroscopic effects of local materials used in new and old buildings can be of interest for engineers. The types of bricks employed in wall construction will also be analysed. Two types of brick materials are employed in Cameroon: parpen and earthen bricks. Owing to the different levels of permeability, they are expected to have some different kinds of effects over the indoor ambience. Other parameters, like permeability level of the wall's external coating were also analysed. To achieve these objectives, 15 office buildings located in the humid and hot region of the capital city of Cameroon were studied during two seasons, in ac-cordance with the procedure developed by Toftum et al.